Which autoantibodies are most commonly associated with autoimmune type 1 diabetes mellitus?

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Multiple Choice

Which autoantibodies are most commonly associated with autoimmune type 1 diabetes mellitus?

Explanation:
Autoimmune type 1 diabetes is marked by antibodies against pancreatic beta-cell components. The antibody against GAD65 is the most commonly detected in people with this condition, found in the majority at diagnosis and can be the only autoantibody present in some cases. IA-2 and ZnT8 antibodies also occur, but less frequently than GAD65, so GAD65 stands out as the best single marker for autoimmune diabetes. Because many patients have more than one autoantibody, a broader panel may be used, but GAD65 is the most commonly associated antibody overall.

Autoimmune type 1 diabetes is marked by antibodies against pancreatic beta-cell components. The antibody against GAD65 is the most commonly detected in people with this condition, found in the majority at diagnosis and can be the only autoantibody present in some cases. IA-2 and ZnT8 antibodies also occur, but less frequently than GAD65, so GAD65 stands out as the best single marker for autoimmune diabetes. Because many patients have more than one autoantibody, a broader panel may be used, but GAD65 is the most commonly associated antibody overall.

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